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Imaging flow cytometry for automated detection of hypoxia-induced erythrocyte shape change in sickle cell disease
In preclinical and early phase pharmacologic trials in sickle cell disease, the percentage of sickled erythrocytes after deoxygenation, an ex vivo functional sickling assay, has been used as a measure of a patient’s disease outcome. We developed a new sickle imaging flow cytometry assay (SIFCA) and...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4180063/ https://ncbi.nlm.nih.gov/pubmed/24585634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23699 |
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