Novel Pyrimidines as Antitubercular Agents

Mycobacterium tuberculosis infection is responsible for a global pandemic. New drugs are needed that do not show cross-resistance with the existing front-line therapeutics. A triazine antitubercular hit led to the design of a related pyrimidine family. The synthesis of a focused series of these anal...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Inoyama, Daigo, Paget, Steven D., Russo, Riccardo, Kandasamy, Srinivasan, Kumar, Pradeep, Singleton, Eric, Occi, James, Tuckman, Margareta, Zimmerman, Matthew D., Ho, Hsin Pin, Perryman, Alexander L., Dartois, Véronique, Connell, Nancy, Freundlich, Joel S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2018
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826157/
https://ncbi.nlm.nih.gov/pubmed/29311070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02063-17
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