Novel Pyrimidines as Antitubercular Agents

Mycobacterium tuberculosis infection is responsible for a global pandemic. New drugs are needed that do not show cross-resistance with the existing front-line therapeutics. A triazine antitubercular hit led to the design of a related pyrimidine family. The synthesis of a focused series of these anal...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Inoyama, Daigo, Paget, Steven D., Russo, Riccardo, Kandasamy, Srinivasan, Kumar, Pradeep, Singleton, Eric, Occi, James, Tuckman, Margareta, Zimmerman, Matthew D., Ho, Hsin Pin, Perryman, Alexander L., Dartois, Véronique, Connell, Nancy, Freundlich, Joel S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826157/
https://ncbi.nlm.nih.gov/pubmed/29311070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02063-17
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