Whole-Cell Screen of Fragment Library Identifies Gut Microbiota Metabolite Indole Propionic Acid as Antitubercular

Several key antituberculosis drugs, including pyrazinamide, with a molecular mass of 123.1 g/mol, are smaller than the usual drug-like molecules. Current drug discovery efforts focus on the screening of larger compounds with molecular masses centered around 400 to 500 g/mol. Fragment (molecular mass...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Negatu, Dereje A., Liu, Joe J. J., Zimmerman, Matthew, Kaya, Firat, Dartois, Véronique, Aldrich, Courtney C., Gengenbacher, Martin, Dick, Thomas
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Experimental Therapeutics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826148/
https://ncbi.nlm.nih.gov/pubmed/29229639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01571-17
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items