Sox2 is required for olfactory pit formation and olfactory neurogenesis through BMP restriction and Hes5 upregulation

The transcription factor Sox2 is necessary to maintain pluripotency of embryonic stem cells, and to regulate neural development. Neurogenesis in the vertebrate olfactory epithelium persists from embryonic stages through adulthood. The role Sox2 plays for the development of the olfactory epithelium a...

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Panaliappan, Tamilarasan K., Wittmann, Walter, Jidigam, Vijay K., Mercurio, Sara, Bertolini, Jessica A., Sghari, Soufien, Bose, Raj, Patthey, Cedric, Nicolis, Silvia K., Gunhaga, Lena
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825848/
https://ncbi.nlm.nih.gov/pubmed/29352015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.153791
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