Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids

Bone morphogenic proteins (BMPs) and the Notch pathway regulate quiescence and self-renewal of stem cells of the subventricular zone (SVZ), an adult neurogenic niche. Here we analyze the role at the intersection of these pathways of Tis21 (Btg2/PC3), a gene regulating proliferation and differentiati...

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Detalhes bibliográficos
Main Authors: Farioli-Vecchioli, Stefano, Ceccarelli, Manuela, Saraulli, Daniele, Micheli, Laura, Cannas, Sara, D’Alessandro, Francesca, Scardigli, Raffaella, Leonardi, Luca, Cinà, Irene, Costanzi, Marco, Mattera, Andrea, Cestari, Vincenzo, Tirone, Felice
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977348/
https://ncbi.nlm.nih.gov/pubmed/24744701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00098
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