Btg1 is Required to Maintain the Pool of Stem and Progenitor Cells of the Dentate Gyrus and Subventricular Zone

Btg1 belongs to a family of cell cycle inhibitory genes. We observed that Btg1 is highly expressed in adult neurogenic niches, i.e., the dentate gyrus and subventricular zone (SVZ). Thus, we generated Btg1 knockout mice to analyze the role of Btg1 in the process of generation of adult new neurons. A...

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Hauptverfasser: Farioli-Vecchioli, Stefano, Micheli, Laura, Saraulli, Daniele, Ceccarelli, Manuela, Cannas, Sara, Scardigli, Raffaella, Leonardi, Luca, Cinà, Irene, Costanzi, Marco, Ciotti, Maria Teresa, Moreira, Pedro, Rouault, Jean-Pierre, Cestari, Vincenzo, Tirone, Felice
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Research Foundation 2012
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431174/
https://ncbi.nlm.nih.gov/pubmed/22969701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2012.00124
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