Btg1 is Required to Maintain the Pool of Stem and Progenitor Cells of the Dentate Gyrus and Subventricular Zone

Btg1 belongs to a family of cell cycle inhibitory genes. We observed that Btg1 is highly expressed in adult neurogenic niches, i.e., the dentate gyrus and subventricular zone (SVZ). Thus, we generated Btg1 knockout mice to analyze the role of Btg1 in the process of generation of adult new neurons. A...

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Bibliografski detalji
Glavni autori: Farioli-Vecchioli, Stefano, Micheli, Laura, Saraulli, Daniele, Ceccarelli, Manuela, Cannas, Sara, Scardigli, Raffaella, Leonardi, Luca, Cinà, Irene, Costanzi, Marco, Ciotti, Maria Teresa, Moreira, Pedro, Rouault, Jean-Pierre, Cestari, Vincenzo, Tirone, Felice
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2012
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431174/
https://ncbi.nlm.nih.gov/pubmed/22969701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2012.00124
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