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Sox2 is required for olfactory pit formation and olfactory neurogenesis through BMP restriction and Hes5 upregulation

The transcription factor Sox2 is necessary to maintain pluripotency of embryonic stem cells, and to regulate neural development. Neurogenesis in the vertebrate olfactory epithelium persists from embryonic stages through adulthood. The role Sox2 plays for the development of the olfactory epithelium a...

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Bibliografiska uppgifter
I publikationen:Development
Huvudupphovsmän: Panaliappan, Tamilarasan K., Wittmann, Walter, Jidigam, Vijay K., Mercurio, Sara, Bertolini, Jessica A., Sghari, Soufien, Bose, Raj, Patthey, Cedric, Nicolis, Silvia K., Gunhaga, Lena
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists Ltd 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825848/
https://ncbi.nlm.nih.gov/pubmed/29352015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.153791
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