Sox2 is required for olfactory pit formation and olfactory neurogenesis through BMP restriction and Hes5 upregulation

The transcription factor Sox2 is necessary to maintain pluripotency of embryonic stem cells, and to regulate neural development. Neurogenesis in the vertebrate olfactory epithelium persists from embryonic stages through adulthood. The role Sox2 plays for the development of the olfactory epithelium a...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Panaliappan, Tamilarasan K., Wittmann, Walter, Jidigam, Vijay K., Mercurio, Sara, Bertolini, Jessica A., Sghari, Soufien, Bose, Raj, Patthey, Cedric, Nicolis, Silvia K., Gunhaga, Lena
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825848/
https://ncbi.nlm.nih.gov/pubmed/29352015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.153791
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