Sox2 is required for olfactory pit formation and olfactory neurogenesis through BMP restriction and Hes5 upregulation

The transcription factor Sox2 is necessary to maintain pluripotency of embryonic stem cells, and to regulate neural development. Neurogenesis in the vertebrate olfactory epithelium persists from embryonic stages through adulthood. The role Sox2 plays for the development of the olfactory epithelium a...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Panaliappan, Tamilarasan K., Wittmann, Walter, Jidigam, Vijay K., Mercurio, Sara, Bertolini, Jessica A., Sghari, Soufien, Bose, Raj, Patthey, Cedric, Nicolis, Silvia K., Gunhaga, Lena
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825848/
https://ncbi.nlm.nih.gov/pubmed/29352015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.153791
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