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Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub
Infection and tissue damage induces assembly of supramolecular organizing centres (SMOCs)), such as the Toll-like receptor (TLR) MyDDosome, to co-ordinate inflammatory signaling. SMOC assembly is thought to drive digital all-or-none responses, yet TLR activation by diverse microbes induces anything...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5825206/ https://ncbi.nlm.nih.gov/pubmed/29368691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31377 |
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