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Role of self-organising myddosome oligomers in inflammatory signalling by Toll-like receptors
Abstract A paper published in BMC Biology characterises biophysically oligomeric and filamentous structures formed spontaneously by the Toll-like receptor signalling adaptor MyD88. Naturally occurring mutants of MyD88 that cause immunodeficiency are unable to form these structures. By contrast a som...
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Autor principal: | |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2019-02-01
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Colecção: | BMC Biology |
Acesso em linha: | http://link.springer.com/article/10.1186/s12915-019-0637-5 |
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