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Role of self-organising myddosome oligomers in inflammatory signalling by Toll-like receptors
A paper published in BMC Biology characterises biophysically oligomeric and filamentous structures formed spontaneously by the Toll-like receptor signalling adaptor MyD88. Naturally occurring mutants of MyD88 that cause immunodeficiency are unable to form these structures. By contrast a somatic muta...
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| Udgivet i: | BMC Biol |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6383289/ https://ncbi.nlm.nih.gov/pubmed/30786893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-019-0637-5 |
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