Regulation of effector Tregs in murine lupus

OBJECTIVE: Tregs need to acquire an effector phenotype to function in inflammatory settings. Whether effector Tregs can limit disease severity in lupus is unknown. IRF4 is an essential controller of effector Tregs and regulates their ability to express IL-10. In non-Tregs, IRF4 activity is modulated...

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Vydáno v:Arthritis Rheumatol
Hlavní autoři: Chandrasekaran, Uma, Yi, Woelsung, Gupta, Sanjay, Weng, Chien-Huan, Giannopoulou, Eugenia, Chinenov, Yurii, Jessberger, Rolf, Weaver, Casey T., Bhagat, Govind, Pernis, Alessandra B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825185/
https://ncbi.nlm.nih.gov/pubmed/26816213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39599
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