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Regulation of effector Tregs in murine lupus
OBJECTIVE: Tregs need to acquire an effector phenotype to function in inflammatory settings. Whether effector Tregs can limit disease severity in lupus is unknown. IRF4 is an essential controller of effector Tregs and regulates their ability to express IL-10. In non-Tregs, IRF4 activity is modulated...
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| Publicado no: | Arthritis Rheumatol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5825185/ https://ncbi.nlm.nih.gov/pubmed/26816213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39599 |
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