Regulation of Age-associated B cells by IRF5 in systemic autoimmunity

Age-associated B cells (ABCs) are a T-bet–dependent B cell subset, which accumulates prematurely in autoimmune settings. The pathways regulating ABCs in autoimmunity are largely unknown. SWAP-70 and DEF6 (also known as IBP or SLAT) are the only two members of the SWEF family, a unique family of Rho...

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Bibliographic Details
Published in:Nat Immunol
Main Authors: Manni, Michela, Gupta, Sanjay, Ricker, Edd, Chinenov, Yurii, Park, Sung Ho, Shi, Man, Pannellini, Tania, Jessberger, Rolf, Ivashkiv, Lionel, Pernis, Alessandra B.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095139/
https://ncbi.nlm.nih.gov/pubmed/29483597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0056-8
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