ToP-DNJ, a Selective Inhibitor of Endoplasmic Reticulum α-Glucosidase II Exhibiting Antiflaviviral Activity

[Image: see text] Iminosugars have therapeutic potential against a range of diseases, due to their efficacy as glycosidase inhibitors. A major challenge in the development of iminosugar drugs lies in making a compound that is selective for the glycosidase associated with a given disease. We report t...

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Bibliografiset tiedot
Julkaisussa:ACS Chem Biol
Päätekijät: Kiappes, J. L., Hill, Michelle L., Alonzi, Dominic S., Miller, Joanna L., Iwaki, Ren, Sayce, Andrew C., Caputo, Alessandro T., Kato, Atsushi, Zitzmann, Nicole
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2017
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824344/
https://ncbi.nlm.nih.gov/pubmed/29161006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00870
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