Inhibitors of Endoplasmic Reticulum α-Glucosidases Potently Suppress Hepatitis C Virus Virion Assembly and Release

α-Glucosidases I and II are endoplasmic reticulum-resident enzymes that are essential for N-linked glycan processing and subsequent proper folding of glycoproteins. In this report, we first demonstrate that downregulation of the expression of α-glucosidase I, II, or both in Huh7.5 cells by small hai...

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Detalhes bibliográficos
Main Authors: Qu, Xiaowang, Pan, Xiaoben, Weidner, Jessica, Yu, Wenquan, Alonzi, Dominic, Xu, Xiaodong, Butters, Terry, Block, Timothy, Guo, Ju-Tao, Chang, Jinhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067080/
https://ncbi.nlm.nih.gov/pubmed/21173177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01319-10
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