Combination of alpha-glucosidase inhibitor and ribavirin for the treatment of Dengue virus infection in vitro and in vivo

Cellular α-glucosidases I and II are enzymes that sequentially trim the three terminal glucoses in the N-linked oligosaccharides of viral envelope glycoproteins. This process is essential for the proper folding of viral glycoproteins and subsequent assembly of many enveloped viruses, including dengu...

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Detalhes bibliográficos
Main Authors: Chang, Jinhong, Schul, Wouter, Butters, Terry D., Yip, Andy, Liu, Boping, Goh, Anne, Lakshminarayana, Suresh B., Alonzi, Dominic, Reinkensmeier, Gabriele, Pan, Xiaoben, Qu, Xiaowang, Weidner, Jessica M., Wang, Lijuan, Yu, Wenquan, Borune, Nigel, Kinch, Mark A., Rayahin, Jamie E., Moriarty, Robert, Xu, Xiaodong, Shi, Pei-Yong, Guo, Ju-Tao, Block, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018560/
https://ncbi.nlm.nih.gov/pubmed/21073903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2010.11.002
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