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α-Glucosidase Inhibitors Reduce Dengue Virus Production by Affecting the Initial Steps of Virion Morphogenesis in the Endoplasmic Reticulum

We report that endoplasmic reticulum α-glucosidase inhibitors have antiviral effects on dengue (DEN) virus. We found that glucosidase inhibition strongly affects productive folding pathways of the envelope glycoproteins prM (the intracellular glycosylated precursor of M [membrane protein]) and E (en...

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Bibliografski detalji
Glavni autori: Courageot, Marie-Pierre, Frenkiel, Marie-Pascale, Duarte Dos Santos, Claudia, Deubel, Vincent, Desprès, Philippe
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC111573/
https://ncbi.nlm.nih.gov/pubmed/10590151
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