Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals

The biosynthesis of enveloped viruses depends heavily on the host cell endoplasmic reticulum (ER) glycoprotein quality control (QC) machinery. This dependency exceeds the dependency of host glycoproteins, offering a window for the targeting of ERQC for the development of broad-spectrum antivirals. W...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Caputo, Alessandro T., Alonzi, Dominic S., Marti, Lucia, Reca, Ida-Barbara, Kiappes, J. L., Struwe, Weston B., Cross, Alice, Basu, Souradeep, Lowe, Edward D., Darlot, Benoit, Santino, Angelo, Roversi, Pietro, Zitzmann, Nicole
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2016
Aiheet:
PNAS Plus
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987793/
https://ncbi.nlm.nih.gov/pubmed/27462106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604463113
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia