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Iminosugar antivirals: the therapeutic sweet spot
Many viruses require the host endoplasmic reticulum protein-folding machinery in order to correctly fold one or more of their glycoproteins. Iminosugars with glucose stereochemistry target the glucosidases which are key for entry into the glycoprotein folding cycle. Viral glycoproteins are thus prev...
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| Publicado no: | Biochem Soc Trans |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5390498/ https://ncbi.nlm.nih.gov/pubmed/28408497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160182 |
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