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Iminosugar antivirals: the therapeutic sweet spot
Many viruses require the host endoplasmic reticulum protein-folding machinery in order to correctly fold one or more of their glycoproteins. Iminosugars with glucose stereochemistry target the glucosidases which are key for entry into the glycoprotein folding cycle. Viral glycoproteins are thus prev...
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| Gepubliceerd in: | Biochem Soc Trans |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Portland Press Ltd.
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5390498/ https://ncbi.nlm.nih.gov/pubmed/28408497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160182 |
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