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Iminosugar antivirals: the therapeutic sweet spot
Many viruses require the host endoplasmic reticulum protein-folding machinery in order to correctly fold one or more of their glycoproteins. Iminosugars with glucose stereochemistry target the glucosidases which are key for entry into the glycoprotein folding cycle. Viral glycoproteins are thus prev...
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| Pubblicato in: | Biochem Soc Trans |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Portland Press Ltd.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5390498/ https://ncbi.nlm.nih.gov/pubmed/28408497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160182 |
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