CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation

Tissue fibrosis is mediated by the actions of multiple pro-fibrotic proteins that can induce myofibroblast phenoconversion through diverse signaling pathways coupled predominantly to Smads or MEK/Erk proteins. The TGFβ/TGFβR and CXCL12/CXCR4 axes induce myofibroblast phenoconversion independently th...

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Sparad:
Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Patalano, Susan, Rodríguez-Nieves, José, Colaneri, Cory, Cotellessa, Justin, Almanza, Diego, Zhilin-Roth, Alisa, Riley, Todd, Macoska, Jill
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823879/
https://ncbi.nlm.nih.gov/pubmed/29472636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21506-7
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