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TRPV4 channel-dependent negative feedback mechanism regulates G(q) protein-coupled receptor-induced vasoconstriction
OBJECTIVE: Several physiological stimuli activate smooth muscle cell (SMC) G(q) protein-coupled receptors (G(q)PCRs) to cause vasoconstriction. As a protective mechanism against excessive vasoconstriction, SMC G(q)PCR stimulation invokes endothelial cell (EC) vasodilatory signalling. Whether Ca(2+)...
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| Vydáno v: | Arterioscler Thromb Vasc Biol |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823749/ https://ncbi.nlm.nih.gov/pubmed/29301784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310038 |
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