Nitric Oxide–Dependent Feedback Loop Regulates Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Cooperativity and Endothelial Function in Small Pulmonary Arteries

BACKGROUND: Recent studies demonstrate that spatially restricted, local Ca(2+) signals are key regulators of endothelium‐dependent vasodilation in systemic circulation. There are drastic functional differences between pulmonary arteries (PAs) and systemic arteries, but the local Ca(2+) signals that...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Marziano, Corina, Hong, Kwangseok, Cope, Eric L., Kotlikoff, Michael I., Isakson, Brant E., Sonkusare, Swapnil K.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5779028/
https://ncbi.nlm.nih.gov/pubmed/29275372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.007157
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