Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia

In cystic fibrosis (CF), deletion of phenylalanine 508 (F508del) in the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel causes misfolding and premature degradation. Considering the numerous effects of the F508del mutation on the assembly and processing of CFTR protein, combi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Tomati, Valeria, Caci, Emanuela, Ferrera, Loretta, Pesce, Emanuela, Sondo, Elvira, Cholon, Deborah M., Quinney, Nancy L., Boyles, Susan E., Armirotti, Andrea, Ravazzolo, Roberto, Galietta, Luis J.V., Gentzsch, Martina, Pedemonte, Nicoletta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821210/
https://ncbi.nlm.nih.gov/pubmed/29415893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98699
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados