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Truncated mu opioid receptors with six transmembrane domains are essential for opioid analgesia
BACKGROUND: Most clinical opioids act through mu opioid receptors. They effectively relieve pain, but are limited by side-effects, such as constipation, respiratory depression, dependence and addiction. Many efforts have been made towards developing potent analgesics lacking side effects. 3-iodobenz...
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| Publicado en: | Anesth Analg |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5820199/ https://ncbi.nlm.nih.gov/pubmed/28991118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000002538 |
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