Optogenetic Activation of Non-Nociceptive Aβ Fibers Induces Neuropathic Pain-Like Sensory and Emotional Behaviors after Nerve Injury in Rats

Neuropathic pain is caused by peripheral nerve injury (PNI). One hallmark symptom is allodynia (pain caused by normally innocuous stimuli), but its mechanistic underpinning remains elusive. Notably, whether selective stimulation of non-nociceptive primary afferent Aβ fibers indeed evokes neuropathic...

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Bibliografske podrobnosti
izdano v:eNeuro
Main Authors: Tashima, Ryoichi, Koga, Keisuke, Sekine, Misuzu, Kanehisa, Kensho, Kohro, Yuta, Tominaga, Keiko, Matsushita, Katsuyuki, Tozaki-Saitoh, Hidetoshi, Fukazawa, Yugo, Inoue, Kazuhide, Yawo, Hiromu, Furue, Hidemasa, Tsuda, Makoto
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2018
Teme:
New Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819669/
https://ncbi.nlm.nih.gov/pubmed/29468190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0450-17.2018
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