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A new minimally-invasive method for microinjection into the mouse spinal dorsal horn

Noninvasive gene delivery to the spinal dorsal horn (SDH) remains challenging because existing methods to directly microinject vectors require laminectomy, which leads to tissue damage and inflammation. Such responses might hamper accurate readouts of cellular and behavioural effects of an introduce...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kohro, Yuta, Sakaguchi, Emi, Tashima, Ryoichi, Tozaki-Saitoh, Hidetoshi, Okano, Hideyuki, Inoue, Kazuhide, Tsuda, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585681/
https://ncbi.nlm.nih.gov/pubmed/26387932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14306
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