A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior

A cardinal, intractable symptom of neuropathic pain is mechanical allodynia, pain caused by innocuous stimuli via low-threshold mechanoreceptors such as Aβ fibers. However, the mechanism by which Aβ fiber-derived signals are converted to pain remains incompletely understood. Here we identify a subse...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Tashima, Ryoichi, Koga, Keisuke, Yoshikawa, Yu, Sekine, Misuzu, Watanabe, Moeka, Tozaki-Saitoh, Hidetoshi, Furue, Hidemasa, Yasaka, Toshiharu, Tsuda, Makoto
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826356/
https://ncbi.nlm.nih.gov/pubmed/33431693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021220118
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