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Optogenetic Activation of Non-Nociceptive Aβ Fibers Induces Neuropathic Pain-Like Sensory and Emotional Behaviors after Nerve Injury in Rats

Neuropathic pain is caused by peripheral nerve injury (PNI). One hallmark symptom is allodynia (pain caused by normally innocuous stimuli), but its mechanistic underpinning remains elusive. Notably, whether selective stimulation of non-nociceptive primary afferent Aβ fibers indeed evokes neuropathic...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Tashima, Ryoichi, Koga, Keisuke, Sekine, Misuzu, Kanehisa, Kensho, Kohro, Yuta, Tominaga, Keiko, Matsushita, Katsuyuki, Tozaki-Saitoh, Hidetoshi, Fukazawa, Yugo, Inoue, Kazuhide, Yawo, Hiromu, Furue, Hidemasa, Tsuda, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819669/
https://ncbi.nlm.nih.gov/pubmed/29468190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0450-17.2018
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