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A High-Throughput Screening Campaign to Identify Inhibitors of DXP Reductoisomerase (IspC) and MEP Cytidylyltransferase (IspD)

The rise of antibacterial resistance among human pathogens represents a problem that could change the landscape of healthcare unless new antibiotics are developed. The methyl erythritol phosphate (MEP) pathway represents an attractive series of targets for novel antibiotic design, considering each e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Anal Biochem
Hauptverfasser: Haymond, Amanda, Dowdy, Tyrone, Johny, Chinchu, Johnson, Claire, Ball, Haley, Dailey, Allyson, Schweibenz, Brandon, Villarroel, Karen, Young, Richard, Mantooth, Clark J., Patel, Trishal, Bases, Jessica, Dowd, Cynthia S., Couch, Robin D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817008/
https://ncbi.nlm.nih.gov/pubmed/29180070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2017.11.018
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