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A High-Throughput Screening Campaign to Identify Inhibitors of DXP Reductoisomerase (IspC) and MEP Cytidylyltransferase (IspD)

The rise of antibacterial resistance among human pathogens represents a problem that could change the landscape of healthcare unless new antibiotics are developed. The methyl erythritol phosphate (MEP) pathway represents an attractive series of targets for novel antibiotic design, considering each e...

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Detalhes bibliográficos
Publicado no:Anal Biochem
Main Authors: Haymond, Amanda, Dowdy, Tyrone, Johny, Chinchu, Johnson, Claire, Ball, Haley, Dailey, Allyson, Schweibenz, Brandon, Villarroel, Karen, Young, Richard, Mantooth, Clark J., Patel, Trishal, Bases, Jessica, Dowd, Cynthia S., Couch, Robin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817008/
https://ncbi.nlm.nih.gov/pubmed/29180070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2017.11.018
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