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The TIA1 RNA-binding-protein family regulates EIF2AK2-mediated stress response and cell cycle progression
TIA1 and TIAL1 encode a family of U-rich element mRNA-binding proteins ubiquitously expressed and conserved in metazoans. Using PAR-CLIP, we determined that both proteins bind target sites with identical specificity in 3′ UTRs and introns proximal to 5′ as well as 3′ splice sites. Double knockout (D...
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| Udgivet i: | Mol Cell |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5816707/ https://ncbi.nlm.nih.gov/pubmed/29429924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.011 |
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