CD209a Synergizes with Dectin-2 and Mincle to Drive Severe Th17 Cell-Mediated Schistosome Egg-Induced Immunopathology

The immunopathology caused by schistosome helminths varies greatly in humans and among mouse strains. A severe form of parasite egg-induced hepatic granulomatous inflammation, seen in CBA mice, is driven by Th17 cells stimulated by IL-1β and IL-23 produced by dendritic cells that express CD209a (SIG...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Kalantari, Parisa, Morales, Yoelkys, Miller, Emily A., Jaramillo, Luis D., Ponichtera, Holly E., Wuethrich, Marcel A., Cheong, Cheolho, Seminario, Maria C., Russo, Joanne M., Bunnell, Stephen C., Stadecker, Miguel J.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815841/
https://ncbi.nlm.nih.gov/pubmed/29386115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.01.001
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