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DENDRITIC CELL EXPRESSION OF THE C-TYPE LECTIN RECEPTOR CD209a: A NOVEL INNATE PARASITE-SENSING MECHANISM INDUCING Th17 CELLS THAT DRIVE SEVERE IMMUNOPATHOLOGY IN MURINE SCHISTOSOME INFECTION
Following infection with the trematode helminth Schistosoma mansoni, CBA mice develop severe parasite egg-induced hepatic granulomatous inflammation as well as prominent CD4(+) T helper 17 (Th17) cell responses driven by dendritic cell (DC)-derived IL-1β and IL-23. By comparison, C57BL/6 mice develo...
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| Publicado no: | Exp Parasitol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618778/ https://ncbi.nlm.nih.gov/pubmed/25913088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2015.04.006 |
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