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Dendritic Cell IL-23 and IL-1 Production in Response to Schistosome Eggs Induces Th17 Cells in a Mouse Strain Prone to Severe Immunopathology

Infection with schistosomes results in a CD4 T cell-mediated inflammatory reaction against parasite eggs that varies greatly in magnitude both in humans as well as in mice. In the murine disease, the severe form of immunopathology correlates with high levels of IL-17. We now report that live schisto...

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Bibliographische Detailangaben
Hauptverfasser: Shainheit, Mara G., Smith, Patrick M., Bazzone, Lindsey E., Wang, Andrew C., Rutitzky, Laura I., Stadecker, Miguel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663362/
https://ncbi.nlm.nih.gov/pubmed/19050275
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