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Genetic Control of Severe Egg-Induced Immunopathology and IL-17 Production in Murine Schistosomiasis

Infection with the trematode parasite Schistosoma mansoni results in a distinct heterogeneity of disease severity, both in humans and in an experimental mouse model. Severe disease is characterized by pronounced hepatic egg-induced granulomatous inflammation in a proinflammatory cytokine environment...

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Detalhes bibliográficos
Main Authors: Smith, Patrick M., Shainheit, Mara G., Bazzone, Lindsey E., Rutitzky, Laura I., Poltorak, Alexander, Stadecker, Miguel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874957/
https://ncbi.nlm.nih.gov/pubmed/19675160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901504
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