Coinfection with the Intestinal Nematode Heligmosomoides polygyrus Markedly Reduces Hepatic Egg-Induced Immunopathology and Proinflammatory Cytokines in Mouse Models of Severe Schistosomiasis

Infection with the trematode helminth Schistosoma mansoni results in a parasite egg-induced, CD4 T-cell-mediated, hepatointestinal granulomatous and fibrosing inflammation that varies greatly in severity, with a higher frequency of milder forms typically occurring in regions where the disease is end...

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Detalhes bibliográficos
Main Authors: Bazzone, Lindsey E., Smith, Patrick M., Rutitzky, Laura I., Shainheit, Mara G., Urban, Joseph F., Setiawan, Tommy, Blum, Arthur M., Weinstock, Joel V., Stadecker, Miguel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573333/
https://ncbi.nlm.nih.gov/pubmed/18710859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00673-08
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