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Ca(2+)-dependent regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis
In inflammatory arthritis, the dysregulation of osteoclast activity by pro-inflammatory cytokines, including TNF, interferes with bone remodeling during inflammation through Ca(2+)-dependent mechanisms causing pathological bone loss. Ca(2+)-dependent CREB/c-fos activation via CaMKIV induces transcri...
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| Vydáno v: | J Immunol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5815326/ https://ncbi.nlm.nih.gov/pubmed/29246953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701170 |
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