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Alternative pathways of osteoclastogenesis in inflammatory arthritis

Osteoclasts are cells of haematopoietic origin that are uniquely specialized to degrade bone. Under physiological conditions, the osteoclastogenesis pathway depends on macrophage colony-stimulating factor 1 (CSF-1, also known as M-CSF) and receptor activator of nuclear factor κB ligand (RANKL). Howe...

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Bibliografiske detaljer
Udgivet i:Nat Rev Rheumatol
Main Authors: Adamopoulos, Iannis E., Mellins, Elizabeth D.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346500/
https://ncbi.nlm.nih.gov/pubmed/25422000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2014.198
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