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Critical role of LTB4/BLT1 in IL-23 induced synovial inflammation and osteoclastogenesis via NF-κB
IL-23 activates the synthesis and production of Leukotriene B4 (LTB4) in myeloid cells, which modulate inflammatory arthritis. In this manuscript we investigate the role of LTB4 and its receptor LTB4R1 (BLT1) in synovial inflammation and osteoclast differentiation. Specifically, we utilized IL-23 in...
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| Udgivet i: | J Immunol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173389/ https://ncbi.nlm.nih.gov/pubmed/27895169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601346 |
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