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Critical role of LTB4/BLT1 in IL-23 induced synovial inflammation and osteoclastogenesis via NF-κB

IL-23 activates the synthesis and production of Leukotriene B4 (LTB4) in myeloid cells, which modulate inflammatory arthritis. In this manuscript we investigate the role of LTB4 and its receptor LTB4R1 (BLT1) in synovial inflammation and osteoclast differentiation. Specifically, we utilized IL-23 in...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Bouchareychas, Laura, Grössinger, Eva M, Kang, Mincheol, Qiu, Hong, Adamopoulos, Iannis E
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173389/
https://ncbi.nlm.nih.gov/pubmed/27895169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601346
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