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The Role of Ca(2+)-NFATc1 Signaling and Its Modulation on Osteoclastogenesis
The increasing of intracellular calcium concentration is a fundamental process for mediating osteoclastogenesis, which is involved in osteoclastic bone resorption. Cytosolic calcium binds to calmodulin and subsequently activates calcineurin, leading to NFATc1 activation, a master transcription facto...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7279283/ https://ncbi.nlm.nih.gov/pubmed/32455661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103646 |
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