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Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1

Adseverin is a Ca(2+)-dependent actin filament-severing protein that has been reported to regulate exocytosis via rearrangements of the actin cytoskeleton in secretory cells. However, the role of adseverin in bone cells has not yet been well characterized. Here, we investigated the role of adseverin...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Song, Min-Kyoung, Lee, Zang Hee, Kim, Hong-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686697/
https://ncbi.nlm.nih.gov/pubmed/26642432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.94
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