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Impaired cohesion and homologous recombination during replicative aging in budding yeast
The causal relationship between genomic instability and replicative aging is unclear. We reveal here that genomic instability at the budding yeast ribosomal DNA (rDNA) locus increases during aging, potentially due to the reduced cohesion that we uncovered during aging caused by the reduced abundance...
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| Udgivet i: | Sci Adv |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Association for the Advancement of Science
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5810620/ https://ncbi.nlm.nih.gov/pubmed/29441364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaq0236 |
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