Impaired cohesion and homologous recombination during replicative aging in budding yeast

The causal relationship between genomic instability and replicative aging is unclear. We reveal here that genomic instability at the budding yeast ribosomal DNA (rDNA) locus increases during aging, potentially due to the reduced cohesion that we uncovered during aging caused by the reduced abundance...

Full description

Saved in:
Bibliographic Details
Published in:Sci Adv
Main Authors: Pal, Sangita, Postnikoff, Spike D., Chavez, Myrriah, Tyler, Jessica K.
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2018
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810620/
https://ncbi.nlm.nih.gov/pubmed/29441364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaq0236
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items