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Is Gcn4-induced autophagy the ultimate downstream mechanism by which hormesis extends yeast replicative lifespan?

The number of times a cell divides before irreversibly arresting is termed replicative lifespan. Despite discovery of many chemical, dietary and genetic interventions that extend replicative lifespan, usually first discovered in budding yeast and subsequently shown to apply to metazoans, there is st...

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Detalhes bibliográficos
Publicado no:Curr Genet
Main Authors: Shen, Zih-Jie, Postnikoff, Spike, Tyler, Jessica K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511304/
https://ncbi.nlm.nih.gov/pubmed/30673825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-019-00936-4
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