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Is Gcn4-induced autophagy the ultimate downstream mechanism by which hormesis extends yeast replicative lifespan?

The number of times a cell divides before irreversibly arresting is termed replicative lifespan. Despite discovery of many chemical, dietary and genetic interventions that extend replicative lifespan, usually first discovered in budding yeast and subsequently shown to apply to metazoans, there is st...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Genet
Hauptverfasser: Shen, Zih-Jie, Postnikoff, Spike, Tyler, Jessica K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511304/
https://ncbi.nlm.nih.gov/pubmed/30673825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-019-00936-4
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