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Design and synthesis of compounds that extend yeast replicative lifespan

This past decade has seen the identification of numerous conserved genes that extend lifespan in diverse species, yet the number of compounds that extend lifespan is relatively small. A class of compounds called STACs, which were identified as activators of Sir2/SIRT1 NAD(+)-dependent deacetylases,...

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Autori principali: Yang, Hongying, Baur, Joseph A., Chen, Allen, Miller, Christine, Sinclair, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545651/
https://ncbi.nlm.nih.gov/pubmed/17156081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2006.00259.x
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