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Design and synthesis of compounds that extend yeast replicative lifespan

This past decade has seen the identification of numerous conserved genes that extend lifespan in diverse species, yet the number of compounds that extend lifespan is relatively small. A class of compounds called STACs, which were identified as activators of Sir2/SIRT1 NAD(+)-dependent deacetylases,...

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Detalhes bibliográficos
Main Authors: Yang, Hongying, Baur, Joseph A., Chen, Allen, Miller, Christine, Sinclair, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545651/
https://ncbi.nlm.nih.gov/pubmed/17156081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2006.00259.x
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