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Characterization of the impact of GMP/GDP synthesis inhibition on replicative lifespan extension in yeast

Slowing down aging-associated accumulation of molecular damage or its prevention represents a promising therapeutic paradigm to combat aging-related disease and death. While several chemical compounds extend lifespan in model organisms, their mechanism of action is often unknown, reducing their ther...

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Detalhes bibliográficos
Publicado no:Curr Genet
Main Authors: Liu, Ping, Sarnoski, Ethan A., Olmez, Tolga T., Young, Thomas Z., Acar, Murat
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367712/
https://ncbi.nlm.nih.gov/pubmed/32232569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-020-01068-w
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