Maintenance of AP-2-Dependent Functional Activities of Nef Restricts Pathways of Immune Escape from CD8 T Lymphocyte Responses

Nef-specific CD8(+) T lymphocytes (CD8TL) are linked to extraordinary control of primate lentiviral replication, but the mechanisms underlying their efficacy remain largely unknown. The immunodominant, Mamu-B*017:01(+)-restricted Nef(195-203)MW9 epitope in SIVmac239 partially overlaps a sorting moti...

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Udgivet i:J Virol
Main Authors: Schouest, Blake, Weiler, Andrea M., Janaka, Sanath Kumar, Myers, Tereance A., Das, Arpita, Wilder, Sarah C., Furlott, Jessica, Baddoo, Melody, Flemington, Erik K., Rakasz, Eva G., Evans, David T., Friedrich, Thomas C., Maness, Nicholas J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Cellular Response to Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809740/
https://ncbi.nlm.nih.gov/pubmed/29237831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01822-17
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