Acute Viral Escape Selectively Impairs Nef-Mediated Major Histocompatibility Complex Class I Downmodulation and Increases Susceptibility to Antiviral T Cells

Nef-specific CD8(+) T lymphocytes (CD8TL) are associated with control of simian immunodeficiency virus (SIV) despite extensive nef variation between and within animals. Deep viral sequencing of the immunodominant Mamu-B*017:01-restricted Nef(165–173)IW9 epitope revealed highly restricted evolution....

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Weiler, Andrea M., Das, Arpita, Akinyosoye, Oluwasayo, Cui, Sherry, O'Connor, Shelby L., Scheef, Elizabeth A., Reed, Jason S., Panganiban, Antonito T., Sacha, Jonah B., Rakasz, Eva G., Friedrich, Thomas C., Maness, Nicholas J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Virus-Cell Interactions
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733980/
https://ncbi.nlm.nih.gov/pubmed/26637459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01975-15
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