Maintenance of AP-2-Dependent Functional Activities of Nef Restricts Pathways of Immune Escape from CD8 T Lymphocyte Responses

Nef-specific CD8(+) T lymphocytes (CD8TL) are linked to extraordinary control of primate lentiviral replication, but the mechanisms underlying their efficacy remain largely unknown. The immunodominant, Mamu-B*017:01(+)-restricted Nef(195-203)MW9 epitope in SIVmac239 partially overlaps a sorting moti...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Schouest, Blake, Weiler, Andrea M., Janaka, Sanath Kumar, Myers, Tereance A., Das, Arpita, Wilder, Sarah C., Furlott, Jessica, Baddoo, Melody, Flemington, Erik K., Rakasz, Eva G., Evans, David T., Friedrich, Thomas C., Maness, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809740/
https://ncbi.nlm.nih.gov/pubmed/29237831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01822-17
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